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Edge Knot City is a city on the west coast of the continental United Cities, and is run by the Homo Demens. The Homo Demens are intent on ensuring Edge Knot City's continued independence, and oppose the UCA's goal of uniting all of the cities in America.
Thought towards the end of Sam Bridges's one-man expedition the Homo Demens attack the city in order to capture Amelie Strand. By the time Sam reaches it, the city is a ravaged ghost town swarming with BTs, cut off from the rest of the USA proper by a massive belt of tar from the other side.
- Edge Knot City is the only Knot city within the Western Region.